Multichannel Amp Impedances

Planning to upgrade my system from stock speakers to a JBL set up. I currently have a subwoofer set up so I’ll be looking to swap my amplifier out for a 5 channel.
4 door speakers
2 subs wired in parallel

Each door speaker will be 75w RMS @ 4 ohms

Subs are 600 RMS @ 2 ohms
- regularly the subs by themselves are 300 RMS @ 4 ohms

I’m looking at the audio control LC-5.1300 because I really like the built in tuner but I’m wondering can I wire a multi channel amp like this with the speakers and subs at different impedances? Or will it bust the amp over time? Been reading a lot on this to better build my knowledge but can’t seem to figure it out.
Let me know anyone if you can!

 

Most amps have an individual power supply for each channel. You can run the channels at whatever impedance you want. My son runs a Champion series Pioneer digital 5 channel amp with the front separates at a 2 ohm load and the rear deck speakers at a 4 ohm load. The subs are also run at 2 ohms. Total power output is 1700 watts peak in this configuration. No issues.

 

Lots of better choices than AC in my opinion…..